可得然胶Curdlan
Wako
Grade: for Biochemistry
Regulation / Hazardous:
Storage condition: Keep at RT.
Manufacturer: Wako
Summary
This product is for research use only. Do not administer it to human.
Curdlan is produced as a water-insoluble polysaccharide by the soil
bacterium, Alcaligenes faecalis var. myxogenes, and was discovered by
Dr. T. Harada at the Institute of Scientific and Industrial Research,
Osaka University. One of the characteristics of Curdlan is that when
the suspension is heated, it becomes a thermally irreversible gel.
Curdlan is used as gel filtration support, affinity chromatography
support, immobilized enzyme support, starch jelly and low calorie food
or a material hardening substance. Curdlan has gained attention as a
research material for gelation mechani*** or as a basic material for
anti-tumor polysaccharide research.
Appearance: White Powder
Structure: Straight chain without branch
Solubility: Insoluble in water and many organic solvents. Freely
soluble in aqueous alkaline solution. Soluble in DMSO and formic acid.
Specific Rotation [A]20/D: +30.0 ~ +35.0
Gel stability: pH 2.0 ~ 9.5 (max. gel strength: pH 2 ~ 3)
USAGE:
Gel filtration and affinity chromatography; Immobilized enzyme
support; Research for mechani*** of gelation; Research for anti-tumor
glucans CM-CURDLAN [Carboxymethyl-beta-1,3-D-glucan]
CM-Curdlan is water soluble beta-1,3-glucan which modified by
carboxymethylation at 40 ~ 80% substitution from Curdlan.
REFERENCES:
T. Harada: Polysaccharides In Food, Butterworths In England, 283
(1979).
Harada, T., Masada, M., Fujimori, K. and I. Maeda, I.: Agric. Biol.
Chem., 30, 196 (1966).
Harada, T., Misaki, A. and Saito, H.: Arch. Biochem. Biophys., 124,
292 (1968).
Hisamatsu, M., Ott, I., Amemura, A., Harada, T., Nakanishi, I. And K.
Kimura.: J. Gen. Microbiol., 103, 375 (1977).
Maeda, I., Saito, H., Masada, M., Misaki, A. and Harada, T.: Agric.
Biol. Chem., 31, 1184 (1967).
Konno, A., Azechi, Y. and Kimura, H.: Agric. Biol. Chem., 43, 101
(1979).
Murooka, Y., Yim, M., Yamada, T. and Harada, T.: Biochim. Biophys.
Acta., 485, 134 (1977).
Kimura, H., Moritaka, S. and Misaki, M.: J. Food Science, 38, 668
(1973).
Takeda, H., Yasuoka, N., Kasai, N., and Harada, T.: Polymer Journal,
10, 365 (1978).
Marchessault, R. H. and Y. Deslandes: Carbohyd. Res., 75, 231 (1979).
Fulton, W. S. and E. D. T. Atkins: ACS Symposium Series, 141, 385
(1980).
Saito, H., Ohki, T. and Sasaki, T.: Biochemistry, 16, 908 (1977).
Harada, T., Koreeda, A., Sato, S. and N. Kasai: J. Electron Microsc.,
28, 147 (1979).
Sasaki, T., Abiko, N., Sugino, Y. and Nitta, K.: Cancer Res., 38, 379
(1978).
Sasaki, T., Abiko, N., Nitta, K., Takasuka, N. and Sugino, Y.:
European J. Cancer, 15, 11 (1979).
Synonym beta-1,3-Glucan
Molecular Formula (-C6H10O5-)n
Appearance: White - slightly brown, powder
Specific Rotation: +30 - +35 degrees(D/20 degrees C) (c=1, dil.
NaOH sol.)
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CM-Curdlan
Wako
Grade: for Biochemistry
Regulation / Hazardous:
Storage condition: Keep at RT.
Manufacturer: Wako
Summary
CM-CURDLAN is water soluble 1,3-beta-glucan which is modified by
carboxymethylation at 40-80% substitution from curdlan.
Synonym CM-curdlan
Carboxymethyl Curdlan
Carboxymethyl-beta-1,3-D-glucan
CAS NO. 114732-86-4
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