PEGylation
PEGylation is an effective method for optimizing biopharmaceutical drugs. Coupling with PEG molecules results in c***iderably greater protease stability, a significant decrease in immunogenicity a perceptible delaying of renal excretion.
Discrete PEG
HPLC analysis of discrete polydisperse PEG:
(A) dPEG is non-dispersed resulting in one single signal
(B) Polydispers PEG reagents are inhomogeneous HPLC analysis of discrete polydisperse PEG: (A) dPEG is non-dispersed resulting in one single signal (B) Polydispers PEG reagents are inhomogeneous
The term "dPEG " is Quanta BioDesign's trademarked acronym for "discrete poly-(ethylene glycol)" or "discrete PEG". Like traditional PEGs, these products contain a hydrophilic, water-soluble backbone c***isting of repeating ethylene oxide units; however unlike traditional PEGs each of our products represents a single compound with a unique, specific, single molecular weight (MW). dPEG products are synthesized from pure building blocks (e.g. triethylene glycol or tetraethylene glycol) in a series of step-wise reacti*** to provide specific MWs, architectures, functional groups, organic moieties suited for a wide variety of applicati***. These products h***e now been used for the modification of therapeutic macromolecules, as linkers in antibody-drug conjugates (ADCs), for bioconjugation of biologics, for surface modification, in diagnostics, to name a few.
Branched-PEG
The unique properties of celares’ branched CelaSYS-reagents are summarized in the following table. The unique properties of celares’ branched CelaSYS-reagents are summarized in the following table.
The technological basis of the CelaSYS product line is a core branching unit to which PEG chains can be attached according to the technical needs. Whereas in traditional PEGylation chain-like structures are attached to the drug molecule, celares GmbH uses branched PEG structures with increased solubility. Furthermore, CelaSYS PEG is the ideal basis for increasing the payload of bio molecules with high potential ***all molecule drugs, e.g. for the manufacturing of antibody drug conjugates (ADCs). In such cases, CelaSYS is structured hetero-bifunctional facilitating the coupling of a defined number of ***all molecule drugs to a biological targeting molecule.
CES0056.1000
CES0058.1000
CES0173.0100
CES0183.0100
CES0216.0100
CES0218.0100
CES0372.1000
QUS10175.0100
QUS10211.0100
QUS10234.0100
QUS10251.0100
QUS10252.0100
QUS10254.1000
QUS10256.1000
QUS10259.1000
QUS10260.0100
QUS10262.0100
QUS10278.0100
QUS10288.0100
QUS10289.0100
QUS10298.0100
QUS10304.0100
QUS10305.0100
QUS10307.0100
QUS10318.0100
QUS10319.0100
QUS10324.0100
QUS10326.0100
QUS10327.0100
QUS10328.0100
QUS10339.0100
QUS10348.0100
QUS10362.0100
QUS10363.0100
QUS10364.0100
QUS10400.0100
QUS10402.0100
QUS10410.0100
QUS10411.0100
QUS10412.0100
QUS10416.0100
QUS10420.0100
QUS10421.0100
QUS10422.0100
QUS10424.0100
QUS10426.0100
QUS10453.0100
QUS10454.0100
QUS10455.0100
QUS10456.0100
QUS10492.0100
QUS10531.0100
QUS10532.0100
QUS10534.0100
QUS10536.0100
QUS10540.0100
QUS10728.0100
QUS10745.0100
QUS10746.0100
QUS10792.0100
QUS10793.0100
QUS10794.0100
QUS10799.0100
QUS10800.0100
QUS10801.0100
QUS10804.0100
QUS10894.0100
QUS10895.0100
QUS10898.0100
QUS10899.0100
QUS10908.0100
QUS10909.0100
QUS10910.0100
QUS10918.0100
QUS10920.0100
QUS10929.0100
QUS10930.0100
QUS10931.0100
QUS10932.0100
QUS10942.0100
4-arm-PEG-Amine
4-arm-PEG-amine
4-arm-PEG-NHS, mono activated
4-arm-PEG-NHS, mono activated
Amino-dPEG 4-(m-dPEG 12)3
Amino-dPEG 4-(m-dPEG 24)3
Amino-dPEG 4-(m-dPEG 4)3
Amino-dPEG 4-(m-dPEG 8)3
Aminooxy-dPEG 12-amido-dPEG 12-(m-dPEG 11)3
Carboxyl-dPEG 4-(m-dPEG 12)3
Carboxyl-dPEG 4-(m-dPEG 24)3
Carboxyl-dPEG 4-(m-dPEG 4)3
Carboxyl-dPEG 4-(m-dPEG 8)3 ester
MAL-dPEG 4-(m-dPEG 24)3
MAL-dPEG 4-(m-dPEG 4)3
MAL-dPEG 4-(m-dPEG 8)3
m-dPEG 11-alcohol
m-dPEG 11-NHS carbonate
m-dPEG 12-acid
m-dPEG 12-amine
m-dPEG 12-azide (NOT SOLD IN THE UNITED STATES OF AMERICA)
m-dPEG 12-lipoic acid
m-dPEG 12-MAL
m-dPEG 12-NHS ester
m-dPEG 12-Propionaldehyde
m-dPEG 12-thiol
m-dPEG 15-alcohol
m-dPEG 15-amine
m-dPEG 15-NHS carbonate
m-dPEG 19-alcohol
m-dPEG 19-NHS carbonate
m-dPEG 23-alcohol
m-dPEG 23-NHS carbonate
m-dPEG 24-acid
m-dPEG 24-amine
m-dPEG 24-azide (NOT SOLD IN THE UNITED STATES OF AMERICA)
m-dPEG 24-lipoic acid
m-dPEG 24-MAL
m-dPEG 24-NHS ester
m-dPEG 24-Propionaldehyde
m-dPEG 2-acid
m-dPEG 2-NHS ester
m-dPEG 2-tosylate
m-dPEG 36-alcohol
m-dPEG 36-amine
m-dPEG 36-azide (Azido-m-dPEG 36) (NOT SOLD IN THE UNITED STATES OF AMERICA)
m-dPEG 36-MAL
m-dPEG 37-acid
m-dPEG 37-NHS ester
m-dPEG 3-NHS carbonate
m-dPEG 48-amine
m-dPEG 48-MAL
m-dPEG 49-NHS ester
m-dPEG 4-acid
m-dPEG 4-alcohol
m-dPEG 4-amine
m-dPEG 4-azide
m-dPEG 4-lipoic acid
m-dPEG 4-MAL
m-dPEG 4-NHS ester
m-dPEG 4-Propionaldehyde
m-dPEG 4-thiol
m-dPEG 4-tosylate
m-dPEG 7-alcohol
m-dPEG 7-NHS carbonate
m-dPEG 7-tosylate
m-dPEG 8-acid
m-dPEG 8-amine
m-dPEG 8-azide
m-dPEG 8-lipoic acid
m-dPEG 8-MAL
m-dPEG 8-NHS ester
m-dPEG 8-Propionaldehyde
m-dPEG 8-thiol
NHS-dPEG 4-(m-dPEG 24)3-ester
NHS-dPEG 4-(m-dPEG 4)3 ester
NHS-dPEG 4-(m-dPEG 8)3 ester
关于YARE:
YARE-PEG修饰性PEG产品特点及技术优势:
我们已经为我们的客户提供了十年的PEG修饰剂服务,我们一直致力于降***格,提高品质!
1、提供多种官能团修饰,性能好,纯度高,产品分子量可定制,产品聚合分散度(PDI)小于 1.05;
2、生产工艺简化,杂质低,品质稳定;
3、批量生产,成本可控;
4、可提供2000多种产品规格;
5、其他特殊规格可提供定制。

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标准品,对照品,NIBSC标准品,抗原,***,标品,英国***生物标准与检定所标品,美国药典,USP,欧洲药典,EP,加拿大TRC,中检所
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聚乙二醇修饰化学和PEG修饰剂选择指南
移液器的日常清洗和维护***
样品瓶和隔垫的选择指南
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