微囊藻***LW,Microcystin LW ,MC-LW,藻***,LW
Product Specification
Identity: |
Identity determined by MS. |
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Formula: |
C54H72N8O12 |
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MW: |
1025.2 |
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Purity: |
≥95% (HPLC) |
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Appearance: |
Whitish film adhered to inside of the vial. |
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CAS: |
157622-02-1 |
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Source/Host: |
Isolated from Microcystis aeruginosa. |
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Solubility: |
Soluble in 100% methanol. |
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Long Term Storage: |
-20°C |
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Hazard: |
HIGHLY IRRITANT. |
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Handling: |
For maximum product recovery after thawing, centrifuge the vial before opening the cap. |
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Background / Technical Information: |
Microcystins are a group of cyclic heptapeptide hepatotoxins produced by a number of cyanobacterial genera. The most notable of which, and namesake, is the widespread genus Microcystis. Structurally, all microcystins c***ist of the generalized structure cyclo(-D-Ala1-X2-D-MeAsp3-Y4-Adda5-D-Glu6-Mdha7-). X and Y are variable L-amino acids, D-MeAsp is D-erythro-ß-methylaspartic acid and Mdha is N-methyldehydroalanine. Adda is the cyanobacteria unique C20 ß-amino acid 3-amino-9-methoxy-2,6,8-trimethyl-10-phenyl-deca-4,6-dienoic acid. Substituti*** of the variable L-amino acids at positi*** 2 and 4 give rise to at least 21 known primary microcystin analogs and alterati*** in the other c***tituent amino acids result in more than 90 reported mycrocystins to date. |