上海惠诚***甾醇 ergosterol 57-87-4

(22E)-Ergosta-5,7,22-trien-3beta-ol

24-Methylch***esta-5,7,22-trien-3b-ol

(22E)-Ergosta-5,7,22-trien-3beta-ol

***甾醇又称***固醇,有***D2的作用。上海惠诚生物提供分析用***甾醇 ergosterol,并提供化学用***甾醇
[α]D20 -110?-132° (c=1, CHCl3)
Ergosterol 化学用    5g,25g
***甾醇是从***类酵母与***菌中发现的一种植物固醇，在紫外线照射下可被转化为***D2。是微生物细胞膜的重要组成部份，对确保细胞膜的完整性，膜结合酶的活性，膜的流动性，细胞活力以及细胞物质运输等起着重要作用。有研究显示***固醇可能具有***特性。
1. Y. Zhang et al. “Requirement for Ergosterol in V-ATPase Function Underlies Antifungal Activity of Azole Drugs” PLoS Pathogens, Vol. 6(6) pp. 1-13, 2010
2. M. Bagnat et al. “Lipid rafts function in biosynthetic delivery of proteins to the cell surface in yeast” PNAS, Vol. 97(7) pp. 3254-3259, 2000
3. K. Grey et al. “Amphotericin primarily kills yeast by simply binding ergosterol” PNAS, doi: 10.1073/pnas.1117280109, 2012
4. T. Takaku et al. “Isolation of an Antitumor Compound from Agaricus blazei Murill and Its Mechani*** of Action” The Journal of Nutrition, Vol. 131(5) pp. 1409-1413, 2001
5. F. Montañés et al. “Repression of ergosterol biosynthesis is essential for stress resistance and is mediated by the Hog1 MAP kinase and the Mot3 and Rox1 transcription factors” Molecular Microbiology, Vol. 79(4) pp. 1008-1023, 2011