兔抗人、大、小鼠等CD34***

中文名称：

兔抗人、大、小鼠等CD34***（细胞表面的唾液粘蛋白）

英文名称：

Anti-CD34

产品编号：

PL030646R

产品规格：

0.1mg/0.2mg

包装情况：

一支包装（原装进口、进口分装）

其他名称：

CD34 antigen; CD34 molecule; Cluster designation 34; Hematopoietic progenitor cell antigen CD34;

背景介绍：

Hematopoietic Stem Cell Marker Endothelial Markers Tumor biomarkers  The highly glycosylated 75-120 kD antigen CD34 is possibly an adhesion molecule with a putative role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. It could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. CD34 is thought to h***e a role in presenting carbohydrate ligands to selectins. The intracellular chain of the CD34 antigen is a site of phosphorylation by activated protein kinase C, suggesting a putative role in signal transduction. Two isoforms of CD34 h***e been reported to be generated by alternative splicing. CD34 is highly expressed on hematopoietic progenitors, as well as on endothelial cells, brain, and testis. Staining for CD34 has been used to measure angiogenesis, which reportedly predicts tumor recurrence.

交叉反应
  物  种：

· Rabbit polyclonal IgG, affinity purified by Protein A.

· Reacts with: hu, rat, mo, cow, pig, dog, Rb