White to off-White Trental Solid Pentoxifylline 99%
Quick Detail:
Pentoxifylline
Allias: Trental, Pentoxil
CAS: 6493-05-6
Purity: 99%
MF: C13H18N4O3
MW: 278.31
EINECS: 229-374-5
Appearance: White to Off-White Solid
Description:
Pentoxifylline is an oral drug used for treating symptoms of intermittent claudication caused by peripheral arterial disease (PAD). Peripheral artery disease is caused by the build-up of cholesterol plaques in arteries of the legs. Plaque blocks arteries, reducing the flow of oxygen-carrying blood through the arteries to the muscles. This causes pain upon walking and reduces mobility. Peripheral artery disease is similar to coronary artery disease in which plaque builds up in heart arteries, causing chest pain (angina) because of a reduced supply of oxygen to the heart's muscle. Pentoxifylline, through unknown mechani***s, decreases the "stickiness" (viscosity) of blood and thereby improves its flow through arteries. This increases the flow of blood and oxygen to muscles and helps patients with intermittent claudication. The FDA approved pentoxifylline in August 1984.
Applicati***:
This medication is used to improve the symptoms of a certain blood flow problem in the legs/arms (intermittent claudication due to occlusive artery disease). Pentoxifylline can decrease the muscle aching/pain/cramps during exercise, including walking, that occur with intermittent claudication. Pentoxifylline belongs to a class of drugs known as hemorrheologic agents. It works by helping blood flow more easily through narrowed arteries. This increases the amount of oxygen that can be delivered by the blood when the muscles need more (such as during exercise) thereby increasing walking distance and duration.
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Pentoxifylline
Identification
Name Pentoxifylline
Synonyms 3,7-Dimethyl-1-(5-oxohexyl)purine-2,6-dione; 3,9-Dimethyl-1-(5-oxohexyl)-2,3,6,9-tetrahydro-1H-purine-2,6-dione
Molecular Structure
Molecular Formula C 13 H 18 N 4 O 3
Molecular Weight 278.31
CAS Registry Number 6493-05-6
EINECS 229-374-5