legal 14484-47-0 Glucocorticoid Recovery Anti Inflammatory Steroids Deflazacort
Synonym: DEFLAZACORT INTERMEDIATE;(4AR,4BS,5S,6AS,9AR,10AS,10BS)-6B-ACETYL-5-HYDROXY-4A,6A,8-TRIMETHYL-4A,4B,5,6,6A,6B,9A,10,10A,10B,11,12-DODECAHYDRO-9-OXA-7-AZA-PENTALENO[2,1-A]PHENANTHREN-2-ONE;Deflazacort;21-Deacetoxy Deflazacort;11beta-Hydroxy-2'-methyl-5'betaH-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione;(11β,16β)-11-hydroxy-2'-Methyl-5'H-Pregna-1,4-dieno[17,16-d]oxazole-3,20-dione;(11β,16β)-11β-hydroxy-2'-Methyl-5βH-Pregna-1,4-dieno[17,16-d]oxazole-3,20-dione;11β-hydroxy-2'-Methyl-5'βH-Pregna-1,4-dieno[17,16-d]oxazole-3,20-dione
CAS No.: 14484-47-0 Formula: C25H31NO6 Molecular Weight: 441.52
EINECS: 238-483-7 Assay: >98% Appearance: white powder
Package: 1kg/foil bag or according to the customers requirements.
Density: 1.41 g/cm3
Melting Point: 255-256.5 °C
Boiling Point: 595.4 °C at 760 mmHg
Flash Point: 313.9 °C
Storage: Keep it under seal in cool and dark place
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Product description:
Deflazacort is a glucocorticoid used as an anti-inflammatory and immunosuppressant.
Deflazacort is an inactive prodrug which is metabolized rapidly to the active drug 21-desacetyldeflazacort. Its potency is around 70-90% that of prednisone.
It is sold in the United Kingdom by Shire under the trade name Calcort; in Brazil as Cortax, Decortil, and Deflanil; in India as MOAID, DFZ, Decotaz, and DefZot; in Panama as Zamen, Spain as Zamene and in Honduras as Flezacor. It is not ***ailable in the United States.
COA:
Product name Deflazacort
Appearance White crystalline powder
Chromatographic purity Any individual impurity not more than 1.0% Total impurities not more than 2.0% 0.4% 1.3%
Loss on drying Not more than 0.5% 0.2%
Residue on ignition Not more than 0.2% 0.03%
Residual solvents Methanol¡Ü3000ppm Methylene Chloride¡Ü600ppm Chloroform¡Ü60ppm Tetrahydrofuran¡Ü720ppm 370ppm Not detect out Not detect out Not detect out
Assay Between 97.0% and 102.0% 99.3%
Micronixation 90% not more than 10 micr*** 90% not more than 10 aicr***